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 Wednesday, February 6, 2008
Plenary
Feb 6, 2008 8:30 AM

Advances in the Management of Treatment-experienced Patients: A 2nd Wave of HAART
Sharon Walmsley
Univ of Toronto, Canada

Plenary
Feb 6, 2008 9:00 AM

New Insights into Retrovirus-Host-cell Interactions
Paul Bieniasz
Aaron Diamond AIDS Res Ctr, The Rockefeller Univ, New York, NY, US

Oral Abstract and Scientific Overview: Drug Delivery, Interactions and Genetic Variability
Feb 6, 2008 10:00 AM

Low Tenofovir Concentrations in Cerebrospinal Fluid
Brookie Best
Univ of California, San Diego, US

Drug Interaction between Antimalarial Drugs and Lopinavir/Ritonavir
Polina German
Univ of California, San Francisco, Sch of Pharmacy, US

Genetic Variation in Accessory Metabolic Pathways Is Associated with Extreme Efavirenz Exposure in Individuals with Impaired CYP2B6 Function
Julia di Iulio
Univ Hosp Ctr, Univ of Lausanne, Switzerland

Long-acting TMC278, a Parenteral Depot Formulation Delivering Therapeutic NNRTI Concentrations in Preclinical and Clinical Settings
Gerben van 't Klooster
Tibotec BVBA, Mechelen, Belgium

Maraviroc Pharmacokinetics in Blood Plasma, Genital Tract Fluid and Tissue in Healthy Female Volunteers
Kristine Patterson
Univ of North Carolina at Chapel Hill, US

The Evolution of Therapeutic Drug Monitoring in ART
Giovanni Di Perri
Univ of Turin, Italy

Oral Abstract: Cardiovascular Risk, Mortality and TB Complicating HIV Infections
Feb 6, 2008 10:00 AM

Elevated Levels of Interleukin-6 and D-dimer Are Associated with an Increased Risk of Death in Patients with HIV
Lewis Kuller
Univ of Pittsburgh, PA, US

HIV Activates Markers of Cardiovascular Risk in a Randomized Treatment Interruption Trial: STACCATO
Alexandra Calmy
Geneva Univ Hosp, Switzerland

Age- and Sex-specific Death Rates in ART-naïve Patients with CD4 Count above 350 cells/mm3 Compared with the General Population
Rebecca Lodwick
Univ Coll London, UK

Immediate vs Deferred ART in the Setting of Acute AIDS-related Opportunistic Infection: Final Results of a Randomized Strategy Trial, ACTG A5164
Andrew Zolopa
Stanford Univ, Palo Alto, CA, US

Exogenous Re-infection with Multidrug- and Extensively Drug-resistant TB among TB/HIV Co-infected Patients in Rural South Africa
Neel Gandhi
Albert Einstein Coll of Med, Bronx, NY, US

HIV Infection and Drug-resistant TB in Ukraine: A Threatening Convergence of 2 Epidemics?
Matteo Zignol
WHO Headquarters, Geneva, Switzerland

The Influence of TB on Early Mortality in the Themba Lethu Clinical Cohort, Johannesburg, South Africa
Daniel Westreich
Univ of North Carolina at Chapel Hill, Sch of Publ Hlth, US

Effects of 18-Month Physiological GH Replacement in Relatively GH-deficient Patients with HIV Lipodystrophy
Steven Grinspoon
Massachusetts Gen Hosp, Boston, US

Oral Abstract: Epidemiology of HIV Infection and Scale-up of ART in Developing Countries
Feb 6, 2008 10:00 AM

Determinants for HIV Acquisition among Adults in Uganda: A Population-based, Nationally Representative Study
Wolfgang Hladik
CDC Uganda, Entebbe

Measuring the Force of the HIV Epidemic in a Rural Area of South Africa: The Africa Centre
Till Barnighausen
Africa Ctr for Hlth and Population Studies, Univ of KwaZulu Natal, Somkhele, South Africa and Harvard Sch of Publ Hlth, Boston, MA, US

Utility of Routine Viral Load, CD4 Cell Count, and Clinical Monitoring among HIV-infected Adults in Uganda: A Randomized Trial
Alex Coutinho
TASO and Infectious Disease Inst, Kampala, Uganda

Long-term CD4 Response to Potent ART among ART-naïve Patients in Several Low-income Countries
Denis Nash
Columbia Univ Mailman Sch of Publ Hlth, New York, NY, US

Evaluation of Clinical and Immunologic Outcomes from the National ART Program in Rwanda, 2004 to 2005
Francois Ndamage
Treatment and Res on AIDS Ctr, Ministry of Hlth, Kigali, Rwanda

Early Detection of Effect on Adult Mortality of a Government ART Program in Rural KwaZulu Natal, South Africa
Graham Cooke
Africa Ctr for Hlth and Population Studies, Univ of KwaZulu Natal, Somkhele, South Africa and Imperial Coll, London, UK

High HIV Prevalence among Males in Discordant Partnerships in a Full Access Door-Door VCT Program in Rural Uganda
E Tumwesigye
Integrated Community Based Initiatives

Oral Abstract: New Insights into Mechanisms of Viral Pathogenecity
Feb 6, 2008 10:00 AM

Preferential Loss of Th17 CD4 T Cells in the Gastrointestinal Tract of HIV-infected Individuals but Not SIV-infected Sooty Mangabeys
Mirko Paiardini
Univ of Pennsylvania, Philadelphia, US

Preferential Loss of Th17 T Cells at Mucosal Sites Predicts Aids Progression in Simian Immunodeficiency Virus-infected Macaques
Valentina Cecchinato
NCI, NIH, Bethesda, MD, US

Primary SIV Infection Causes Rapid Loss of the Balance between TH17 and T Regulatory Cell Populations in Pathogenic Infection of Non-human Primates
David Favre
Univ of California, San Francisco, US

Bacterial DNA Are Measurable in Plasma of HIV-infected Patients and Are Diminished by ART
Wei Jiang
Case Western Reserve Univ, Cleveland, OH, US

SIVrcm, a Unique CCR2-tropic Virus, Selectively Depletes Memory CD4+ T Cells in Pigtail Macaques Due to Rapid Co-receptor Expansion in vivo
Rajeev Gautam
Tulane Natl Primate Res Ctr, Covington, LA, US

Evidence for Persistent Viral Replication in Lymph Node and GALT of ARV-treated Persons
Timothy Schacker
Univ of Minnesota, Minneapolis, US

HIV-1 Rebound during ART Interruption Is Associated with a Preferential Depletion of CD4+ T Cells from the Gastrointestinal Tract.
Saurabh Mehandru
Aaron Diamond AIDS Res Ctr, The Rockefeller Univ, and Mt Sinai Sch of Med, New York, NY, US

Syndecan-3 Is a Dendritic Cell-specific Attachment Receptor for HIV-1
Lot De Witte
VU University Medical Center, The Netherlands

Symposium: Accessory Proteins and Intrinsic Resistance
Feb 6, 2008 4:00 PM

Vif and APOBEC: What We Know
Xiao-Fang Yu
Johns Hopkins Univ, Baltimore, MD, US

The Role of Vpu in Retrovirus Particle Release
Paul Spearman
Emory Univ Sch of Med, Atlanta, GA, US

Genetic Variation in TRIM5alpha and Related Genes
Sara Sawyer
Univ of Texas, Austin, US

HIV Vpr Protein as a Mediator of Ubiquitylation
Carlos de Noronha
Albany Med Coll, NY, US

Symposium: Frontiers in Vaccine Research
Feb 6, 2008 4:00 PM

Lessons Learned from HIV-1 Envelope Glycoprotein Immunogenicity Analysis
Richard Wyatt
Vaccine Res Ctr, NIAID, NIH, Bethesda, MD, US

Identification and Characterization of Transmitted and Early Founder Viruses in Primary HIV-1 Infection
George Shaw
Univ of Alabama at Birmingham, US

Attenuated SIV Models and Protection from Pathogenic Heterologous Challenges
James Hoxie
Univ of Pennsylvania Sch of Med, Philadelphia, US

Symposium: Individualizing Patient Management
Feb 6, 2008 4:00 PM

Optimizing Patient Management in Resource-limited Settings
Jonathan Mermin
CDC Kenya, Nairobi

Individualizing Patient Management: Host Genetics
Jacques Fellay
Duke Univ, Durham, NC, US

Individualized Management of Therapy: Virologic Complications
Carlo-Federico Perno
Univ of Rome Tor Vergata, Italy

Individualized Management of Therapy: The Issue of Complications
Jennifer Hoy
Alfred Hosp, Monash Univ, Melbourne, Australia