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 Monday, February 4, 2008
Plenary
Feb 4, 2008 8:30 AM

Morbidity and Mortality in the HAART Era
Andrew Phillips
Royal Free and Univ Coll Med Sch, Univ Coll London, UK

Plenary
Feb 4, 2008 9:00 AM

Searching the Genome for Determinants of Response to HIV
David Goldstein
Duke Univ, Durham, NC, US

Oral Abstract: Epidemiology of SIV/HIV Infection and AIDS-related Malignancies
Feb 4, 2008 10:00 AM

Geographic Distribution of SIVgor in Wild-living Gorillas from Cameroon
Cecile Neel
UMR145, Inst for Res and Devt, Univ of Montpellier 1, France and PRESICA, Yaounde, Cameroon

Diagnosis and Monitoring of HIV-1 Group O Infections in Cameroun
AurElia Vessiere
Ctr Pasteur of Cameroon, Yaounde

New and Old Complex Recombinant HIV-1 Strains Entering in France among Patients with Primary Infection in 2004 to 2006: Tthe French ANRS CO06 Primo Cohort Study
Marie-Laure Chaix
Ctr Hosp Univ Necker, Paris, France

Recent Phylodynamics of the HIV Epidemic among MSM in the United Kingdom
Gareth Hughes
Univ of Edinburgh, Scotland

Changes Over Time in the Risk of Death following HIV Seroconversion Compared with Mortality in the General Population
Kholoud Porter
Med Res Council Clinical Trials Unit, London, UK

Immunodeficiency and Risk of AIDS-defining and Non-AIDS-defining Cancers: ANRS CO3 Aquitaine Cohort, 1998 to 2006
Fabrice Bonnet
INSERM U593 and CIC-EC7, Ctr Hosp Univ, Univ Victor Segalen, Bordeaux, France

Insufficient Virus Suppression during HAART Is a Strong Predictor for the Development of AIDS-related Lymphoma: German CLINSURV Cohort
Alexander Zoufaly
Univ Med Ctr Hamburg-Eppendorf, Germany

Oral Abstract: New Antiretrovirals and Clinical Trials
Feb 4, 2008 10:00 AM

Structure of HIV-1 CAN in Complex with CAP-1, an Assembly Inhibitor
Brian Kelly
Univ of Utah, Salt Lake City, US

A Prospective, Randomized, Controlled, Open-label Trial Evaluating the Effect of Therapeutic Drug Monitoring and Protease Inhibitor Dose Escalation on Viral Load Responses in Antiretroviral-experienced, HIV-infected Patients with a Normalized Inhibitory
Lisa Demeter
Univ of Rochester Sch of Med Dentistry, NY, US

Re-initiation of ART in the CD4-guided ART Interruption Group in the SMART Study Lowers Risk of Opportunistic Disease or Death
Wafaa El-Sadr
Harlem Hosp Ctr, Columbia Univ, New York, NY, US

Efficacy and Safety of Once-daily Atazanavir/Ritonavir Compared to Twice-daily Lopinavir/Ritonavir, Each in Combination with Tenofovir and Emtricitabinein ARV-naive HIV-1-infected Subjects. The CASTLE Study, 48-week Results
Jean-Michel Molina
Hosp St Louis, Paris, France

Safety and Activity of SCH532706, a Small Molecule Chemokine Receptor 5 Antagonist in HIV-1-infected Individuals
Sarah Pett
Natl Ctr for HIV Epidemiology and Clin Res, Univ of New South Wales, Australia

Vicriviroc, a Next Generation CCR5 Antagonist, Exhibits Potent, Sustained Suppression of Viral Replication in Treatment-experienced Adults: VICTOR-E1 48-week Results
Barry Zingman
Montefiore Med Ctr, Bronx, NY, US

Virological Correlates Associated with Treatment Failure at Week 48 in the Phase 3 Study of Maraviroc in Treatment-naïve Patients
Mike Westby
Pfizer Global R&D, Sandwich, UK

Trends in Second Virologic Failure and Predictors of Subsequent Mortality among ART-experienced Patients: North American Experience
Richard Moore
The North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD) of the IeDEA

Oral Abstract: Prevention Strategies
Feb 4, 2008 10:00 AM

Comprehensive Pre-clinical Assessment of Microbicide Safety Using in vitro and Murine Models
Pedro Mesquita
Albert Einstein Coll of Med, Bronx, NY, US

Protective Effect of Vaginal Lactobacillus on Genital HIV-1 RNA Concentrations: Longitudinal Data from a US Cohort Study
Jane Hitti
Univ of Washington, Seattle, US

Trial of Male Circumcision: Prevention of HSV-2 in Men and Vaginal Infections in Female Partners, Rakai, Uganda
Aaron Tobian
Johns Hopkins Univ, Baltimore, MD, US

3-Year Follow-up of Sexual Behavior and HIV Transmission Risk of Persons Taking ART in Rural Uganda
Rebecca Bunnell
Global AIDS Prgm, CDC Uganda, Kampala

Serosorting, but Not Seropositioning, Is Associated with Decreased Risk of HIV Seroconversion in the EXPLORE Study Cohort
Susan Philip
San Francisco Dept of Publ Hlth, CA, US

HSV-2 Suppressive Therapy for Prevention of HIV Acquisition: Results of HPTN 039
Connie Celum
Univ of Washington, Seattle, US

Trial of Male Circumcision in HIV+ Men, Rakai, Uganda: Effects in HIV+ Men and in Women Partners
Maria Wawer
Johns Hopkins Univ Bloomberg Sch of Publ Hlth, Baltimore, MD, US

Oral Abstract: Viral Pathogenesis and Immune Surveillance
Feb 4, 2008 10:00 AM

Patterns of CD8+ Immunodominance May Influence the Ability of Mamu-B*08+ Macaques to Naturally Control SIVmac239 Replication
John Loffredo
Wisconsin Natl Primate Res Ctr, Univ of Wisconsin, Madison, US

CD20+ Cell Depletion Results in Abbreviated Cell-mediated Immune Responses, Higher Viral Set-points and Shortened Survival in SIV-infected Pigtailed Macaques
Lu-Ann Pozzi
New England Primate Res Ctr, Harvard Med Sch, Southborough, MA, US

Humoral Immune Responses Have Little Effect on Controlling Viremia during SIVagm Infection of African Green Monkeys
Thaidra Gaufin
Tulane Natl Primate Res Ctr, Covington, LA, US

Experimentally Induced Immune Activation in Natural Hosts of SIV Results in Significant Increases in Viral Replication
Ivona Pandrea
Tulane Natl Primate Res Ctr, Tulane Univ, Covington, LA, US

Depletion of CD8+ T Cells Does Not Change the in vivo Life Span of Infected Cells during Pathogenic SIV Infection of Rhesus Macaques
Nichole Klatt
Univ of Pennsylvania, Philadelphia, US and Yerkes Natl Primate Res Ctr, Emory Univ, Atlanta, GA, US

Functionality of HIV-1-specific CD8+ T Cells Is Dependent on Antigen Load and Sequence Diversification
Hendrik Streeck
Partners AIDS Res Ctr, Massachusetts Gen Hosp, Harvard Med Sch, Boston, US

Kinetics of Escape within HLA-restricted CTL Epitopes in the First Year of HIV Infection Is Consistent with Early Immunodominant CTL Response Patterns
Zabrina Brumme
Partners AIDS Res Ctr, Boston, MA, US

A New Factor Involved in HIV Epitope Processing Efficiency: Intracellular Epitope Stability
Estibaliz Lazaro
Partners AIDS Res Ctr, Massachusetts Gen Hosp, Harvard Med Sch, Boston, US

Mapping Escape Mutations Arising under HLA-restricted CTL Selection Pressure in HIV-1 Gag: Correlations with Plasma Viral Load and CD4 Count in Untreated Chronic Infection
Chanson Brumme
Partners AIDS Res Ctr, Boston, MA, US

Oral Abstract: Hepatitis Co-infection
Feb 4, 2008 4:00 PM

HIV Entry and Replication in Stellate Cells Promotes Cellular Activation and Fibrogenesis: Implications for Hepatic Fibrosis in HIV/HCV Co-infection
Ana Tuyama
Mt Sinai Sch of Med, New York, NY, US

HIV-related Microbial Translocation, a Mechanism for Liver Disease
Stuart Ray
Johns Hopkins Med Inst, Baltimore, MD, US

Sustained Long-term Antiviral Maintenance with Pegylated Interferon in HCV/HIV-co-infected Patients: Early Viral Response and Effect on Fibrosis in Treated and Control Subjects
Kenneth Sherman
Univ of Cincinnati, OH, US

Sustained Virological Response to Interferon plus Ribavirin Reduces Liver-related Complications and Mortality in HIV/HCV-co-infected Patients
Juan Berenguer
Hosp Gregorio Maranon, Madrid, Spain

Hepatitis C Viremia following Sustained Virological Response to Pegylated Interferon and Ribavarin in HIV+ Men Who Have Sex with Men-Re-infection or Late Relapse?
Rachael Jones
Chelsea and Westminster NHS Fndn Trust, London, UK

3 Interlinked Mechanisms of Inhibition of HIV-1 Reverse Transcriptase by the HBV Drug Entecavir
Egor Tchesnokov
McGill Univ, Montreal, Canada

The Anti-HIV Activity of Entecavir: Serum HIV RNA Decreases and Selection of the M184V Mutation Occurs in both ART-naïve and -experienced HIV/HBV-co-infected Individuals
Jennifer Audsley
Alfred Hosp, Monash Univ, CCREID, Univ of Melbourne, Melbourne, Australia

MELD is the Best Predictor of Pre-transplant Mortality in HIV-infected Liver Transplant Candidates
Aruna Subramanian
Johns Hopkins Univ, Baltimore, MD US

Oral Abstract: PMTCT
Feb 4, 2008 4:00 PM

Extended Infant Post-exposure Prophylaxis with Antiretroviral Drugs Significantly Reduces Postnatal HIV Transmission: The PEPI-Malawi Study
Taha Taha
Johns Hopkins Univ Bloomberg Sch of Publ Hlth, Baltimore, MD, US

Extended-dose Nevirapine to 6 Weeks of Age for Infants in Ethiopia, India and Uganda: A Randomized Trial for Prevention of HIV Transmission through Breastfeeding
Jayagowri Sastry
BJ Med Coll, Pune, India and Johns Hopkins Univ, Baltimore, MD, US; and Addis Ababa Univ Faculty of Med, Ethiopia; and Makerere Univ Sch of Med, Kampala, Uganda

Timing of Infection Is Critical for Nevirapine Resistance Outcomes among Breastfed Subtype C HIV-1-infected Infants Exposed to Extended vs Single-dose Nevirapine Prophylaxis: The India SWEN Study
Anitha Moorthy
Johns Hopkins Univ Bloomberg Sch of Publ Hlth, Baltimore, MD, US

PMTCT of HIV-1 among Breastfeeding Mothers Using HAART: The Kisumu Breastfeeding Study, Kisumu, Kenya, 2003-2007
Timothy Thomas
CDC Kenya, Kisumu

The TEmAA ANRS 12109 Phase II Trial, Step 1: Tolerance and Viral Resistance after Single-dose Nevirapine and Short-course of Tenofovir Dsoproxil Fumarate and Emtricitabine to Prevent Mother-to-Child Transmission of HIV-1
Elise Arrive
INSERM U593, Inst for Publ Hlth, Epi and Devt, Univ Victor Segalen, Bordeaux, France

Duration and Pattern of Breastfeeding and Postnatal Transmission of HIV: Pooled Analysis of Individual Data from a West and South African Cohort Study
Renaud Becquet
Africa Ctr for Hlth and Population Studies, Univ of KwaZulu Natal, Somkhele, South Africa and INSERM U593, Inst for Publ Hlth, Epi and Devt, Univ Victor Segalen, Bordeaux, France

Population Pharmacokinetics of Tenofovir in HIV-1-infected Pregnant Women and Their Neonates: TEmAA ANRS 12109
Deborah Hirt
Hosp Cochin, France

Effectiveness of NNRTI-containing ART in Women Previously Exposed to a Single Dose of Nevirapine: A Multi-country Cohort Study
Paul Weidle
CDC, Atlanta, GA, US

Symposium: Curbing the US Epidemic
Feb 4, 2008 4:00 PM

What's Driving the US Epidemic in Men Who Have Sex with Men
Ronald Stall
Univ of Pittsburgh Sch of Publ Hlth, PA, US

What's Driving the US Epidemic among Women
Adaora Adimora
Univ of North Carolina at Chapel Hill, US

Prevention for Positives
Simon Rosser
Univ of Minnesota, Minneapolis, US

Addressing Substance Abuse
David Vlahov
New York Academy of Med, NY, US

Symposium: Voyages through the Cell: Imaging Viral Traffic
Feb 4, 2008 4:00 PM

Pre-integration Complex Transport to the Nucleus
Nathalie Arhel
Pasteur Inst, Paris, France

Live Imaging of Cell-to-Cell Transmission of Retroviruses
Walther Mothes
Yale Univ, New Haven, CT, US

Electron Cryotomography of HIV Virions
Grant Jensen
California Inst of Tech, Pasadena, US

Electron Tomography of Immunodeficiency Viruses and Structural Mechanisms of Cellular Entry
Sriram Subramaniam
Ctr for Cancer Res, NCI, NIH, Bethesda, MD, US