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 Wednesday February 28, 2007
Plenary
Feb 28, 2007 8:30 AM

Pathogenesis of Immune Reconstitution Inflammatory Syndrome
Martyn French
Royal Perth Hosp, Univ of Western Australia

Plenary
Feb 28, 2007 9:00 AM

Viruses, microRNAs and RNA Interference
Bryan Cullen
Duke Univ Med Ctr, Durham, NC, US

Oral Abstracts & Scientific Overview: HIV Infection in the Brain: Predictors, Risk Factors, and the Impact of HAART
Feb 28, 2007 10:00 AM

This Is Your Brain Off Drugs: Neurocognitive Function before and after ART Discontinuation in Patients with High CD4 Nadir (ACTG A5170)
Kevin Robertson
Univ of North Carolina at Chapel Hill, US

HIV-1-associated Dementia Associated with HIV DNA within Monocytes in Subjects Treated or Not Treated with ARV Medications
Bruce Shiramizu
Univ of Hawaii John A Burns Sch of Med, Honolulu, US

Predictors of Cerebrospinal Fluid Viral Burden during Primary HIV-1 Infection
Serena Spudich
Univ of California, San Francisco, US

MRS Can Detect HIV-induced Inflammation and Oxidative Stress in the Lenticular Nuclei
Beau Ances
Univ of California, San Diego, US

Longitudinal Stability of Psychomotor Speed and Cognitive Flexibility in Long-term Asymptomatic HIV-infected Individuals
Michael Cole
Univ of California, Los Angeles Med Ctr, US

Altered Diffusion Scalar Metrics in the Midsagittal Corpus Callosum Are Associated with Cognition among HIV Patients
David Tate
Ctr for AIDS Res, The Miriam Hosp, Providence, RI, US

Progressive Multifocal Leukoencephalopathy in the Era of HAART
David Clifford
Washington Univ, St Louis, MO, US

Oral Abstracts: Clinical Trials, Predictors of Outcome, and Disparities in Care
Feb 28, 2007 10:00 AM

Initial Viral Decay to Assess the Relative Antiretroviral Potency of PI-, NNRTI-, and NRTI-Sparing Regimens for First Line Therapy of HIV-1 Infection: ACTG 5160s
Richard H. Haubrich
Univ of California, San Diego, US

Randomized Comparison in Treatment-naïve Patients of Once-daily vs Twice-daily Lopinavir/ritonavir-based ART and Comparison of Once-daily Self-administered vs Directly Observed Therapy
Robert Gross
Univ of Pennsylvania Sch of Med, Philadephia, US

Comparison of Plasma HIV-1 RNA, CD4 Cell Count, and CD38 Expression on CD8 T Cells as Predictors of Progression to AIDS and CD4 Cell Decline among Untreated Participants in the Multicenter AIDS Cohort Study
John Mellors
Univ of Pittsburgh, PA, US

Predictive Value of Plasma HIV RNA Levels for Rate of CD4 Decline and Clinical Disease Progression
Bryan Lau
Johns Hopkins Univ, Baltimore, MD, US

Carriage of HLA-Bw4 Is associated with lower CD4 Cell Counts after Starting HAART: Consistent Findings in the Western Australian HIV Cohort Study and the Swiss HIV Cohort Study
Andri Rauch
Univ Hosp, Berne, Switzerland

Disparities in Survival Attributable to Suboptimal HIV Care in the US: Influence of Gender and Race/Ethnicity
Elena Losina
Massachusetts Gen Hosp, Boston, US and Boston Univ Sch of Publ Hlth, MA, US

The HIV Integrase Inhibitor GS-9137 Demonstrates Potent ARV Activity in Treatment-experienced Patients
Andrew Zolopa
Stanford Univ, CA, US

48-Week Primary Analysis of Trial TMC278-C204: TMC278 Demonstrates Potent and Sustained Efficacy in ART-naïve Patients
Anton Pozniak
Chelsea and Westminster Hosp, London, UK

Oral Abstracts: Hepatitis B and C: Epidemiology, Pathogenesis, and Treatment
Feb 28, 2007 10:00 AM

Acute Hepatitis C in Men Who Have Sex With Men Is Not Confined to Those Infected with HIV, and Their Number Continues to Increase
Daniel Richardson
Royal Sussex County Hosp, Brighton, UK

The Dynamics of HCV Transmission among Injection Drug Users in St. Petersburg, Russia: Sexual Transmission and Acquisition of HIV Cooperative Agreement Program
Elijah Paintsil
Yale Univ, New Haven, CT, US

HCV-specific CD8+ T Cells Produce TGF-β that Suppresses HCV-specific T-cell responses of HCV-mono-infected and HIV-co-infected Subjects
Nadia Alatrakchi
Beth Israel Deaconess Med Ctr, Harvard Med Sch, Boston, MA, US

HIV-specific T Cells Accumulate in the Liver in HCV/HIV Co-infection
Mario Ostrowski
Univ of Toronto, Canada

CpG Adjuvant + HBV Vaccination in HIV Infection Achieves Long-term Seroprotection for as Long as 5 Years
Curtis Cooper
Ottawa Hosp, Univ of Ottawa, Canada

Selection of HBV-resistant Mutants in HIV/HBV-co-infected Patients Failing ART with Anti-HBV Activity: Implications for Diagnostic and Vaccine Escape
Julie Sheldon
Hosp Carlos III, Madrid, Spain

The Anti-Hepatitis B Drug Entecavir Inhibits HIV-1 Replication and Selects HIV-1 Variants Resistant to ARV Drugs
Chloe Thio
Johns Hopkins Univ, Baltimore, MD, US

Oral Abstracts: Primary HIV Infection, Early Treatment, and Immune-Based Therapies for Chronic Infection
Feb 28, 2007 10:00 AM

HIV in Genital Fluids during Heterosexual Transmission
Debrah Boeras
Emory Univ, Atlanta, GA, US

Complex HIV-1 Populations Prior to Seroconversion in Men Who Have Sex with Men: Analysis of HIV-1 Plasma RNA Positive-Seronegative Subjects from the MACS
Geoffrey Gottlieb
Univ of Washington, Seattle, US

HIV-1 Envelopes from Acute and Chronic Infection Differ in Their Levels of Fusogenicity and Sensitivity to Inhibition with sCD4
Terri Wrin
Monogram Biosci, South San Francisco, CA, US

Immunodomination by HLA-B27- and HLA-B57-restricted HIV-1-specific T-cell Responses Results in Abrogation of other HLA-restricted Responses in Primary HIV-1 Infection
Hendrik Streeck
Partners AIDS Res Ctr, Massachusetts Gen Hosp, Harvard Med Sch, Boston, US

Early Treatment of Primary HIV-1 Infection Lowers the Viral Set Point
Radjin Steingrover
Academic Med Ctr, Univ of Amsterdam, The Netherlands

No Benefit from Early Treatment in Primary HIV-infection?
Christine Koegl
IMUC Res, Munich, Germany

Time to ART Resumption following Treatment Interruption Is Shorter for Individuals Immunized with HIV-Recombinant Canarypox Vaccine (Vcp1452) Compared to Placebo: The Manon-02 Trial
Brigitte Autran
Hosp Pitie-Salpetriere, Paris, France; Univ Pierre et Marie Curie, Paris, France; INSERM U543, Paris, France;

Repeated r-hIL-7 Doses Improve T-cell Recovery in HIV-1-infected Patients Enrolled in a Phase I/II Multicentric Study
Y. Levy
INSERM, Creteil, France and Henri Mondor Hosp, Creteil, France

rhIL7 in HIV-1-infected Subjects with CD4 T-cell Count >100cells/µL and Viral Load <50,000 copies/mL: Results from a Randomized, Placebo-controlled, Double-blinded Study (ACTG5214)
Irini Sereti
NIAID, NIH, Bethesda, MD, US

In Chronic HIV-1 infection, Cyclosporine A Provides No Sustained Immunologic Benefit to Persons Starting ART
Michael Lederman
Case Western Reserve Univ, Cleveland, OH, US

Oral Abstracts: Epidemiology: Transmission Dynamics and Risk
Feb 28, 2007 4:00 PM

Exodus and Genesis: The Emergence of HIV-1 Group M Subtype B
Michael Worobey
Univ of Arizona, Tucson, US

HIV-1 Transmission Dynamics in an Urban North American Setting
Bluma Brenner
McGill AIDS Ctr, Jewish Gen Hosp, Montreal, Canada

Despite HAART, HIV-1 Is Once again Spreading Epidemically among Men Having Sex with Men in the Netherlands
Daniela Bezemer
HIV Monitoring Fndn, Amsterdam, The Netherlands

Correlates of Incident HIV Diagnosis, Knowledge of Chemoprophylaxis, and Burden of Acute and Recent Infection among Patrons of New York City Bathhouses: A Pilot Study
Demetre Daskalakis
New York Univ Sch of Med, NY, US

Population-based Prevalence Estimates of Diagnosed and Undiagnosed HIV and Associated Risk Behaviors among New York City Adults, 2004
Trang Quyen Nguyen
New York City Dept of Hlth and Mental Hygiene, New York, NY, US and CDC, Atlanta, GA, US

Impact of HSV-2 Suppressive Therapy on Genital and Plasma HIV-1 RNA in HIV-1 and HSV-2-seropositive Women Not Taking ART: A Randomized, Placebocontrolled Trial in Johannesburg, South Africa
Sinead Delany
Reproductive Hlth and HIV Res Unit, Johannesburg, South Africa and London Sch of Hygiene and Tropical Med, UK;

Randomized Trial of Male Circumcision for HIV Prevention in Rakai, Uganda
Ronald Gray
Johns Hopkins Univ Bloomberg Sch of Publ Hlth, Baltimore, MD, US

The Effects of Male Circumcision on Genital Ulcer Disease and Urethral Symptoms, and on HIV Acquisition: An RCT in Rakai, Uganda
Maria Wawer presented by Ronald Gray
Johns Hopkins Univ Bloomberg Sch of Publ Hlth, Baltimore, MD, US

Symposium: Hepatitis Co-Infection: Mechanisms and Impact
Feb 28, 2007 4:00 PM

Immunopathogenesis of Acute and Chronic Viral Hepatitis C
Barbara Rehermann
Natl Inst of Diabetes & Digestive & Kidney Diseases, NIH, Bethesda, MD, US

Staging Liver Disease in HIV/HCV-co-infected Persons: Is Liver Biopsy the Right Test?
David Thomas
Johns Hopkins Univ Sch of Med, Baltimore, MD, US

Treating Hepatitis C in HIV-infected Patients: Is Now the Right Time?
Raymund Chung
Massachusetts Gen Hosp, Boston, US

Managing HBV Infection in 2007
Chloe Thio
Johns Hopkins Univ, Baltimore, MD, US

Symposium: Immunopathogenesis: T-Cell Activation and CD4 T-Cell Dysfunction
Feb 28, 2007 4:00 PM

The Role of Nef in Primate Lentiviral Pathogenesis
Frank Kirchhoff
Univ of Ulm, Germany

Immunoregulation in HIV Infection
Bruce Walker
Partners AIDS Res Ctr, Massachusetts Gen Hosp, Boston, US

Understanding the Benign Nature of SIV Infection in Natural Hosts: Implications for AIDS Pathogenesis
Guido Silvestri
Univ of Pennsylvania Sch of Med, Philadephia, US

Interactions between Regulatory T Cells and HIV: a Complex Balancing Act
Claire Chougnet
Cincinnati Children's Hosp Res Fndn, OH, US

Symposium: Management of HIV and Sexual Risk in Adolescents
Feb 28, 2007 4:00 PM

HIV among Adolescents and Young Adults in the US and Implications for Biomedical Prevention Trials
Jonathan Ellen
Johns Hopkins Univ Sch of Med, Baltimore, MD, US

The Prime of Our Lives: Immunological Fitness and Reconstitution in Adolescence and Early Adulthood
Paul Krogstad
David Geffen Sch of Med, Univ of California, Los Angeles AIDS Inst, US

Targeting Adolescents for HIV Vaccine Trails in South Africa
Glenda Gray
Univ of the Witwatersrand, Chris Hani Baragwanath Hosp, Soweto, South Africa

HPV-associated Cancers and HIV: Will HPV Vaccines Make a Difference?
Anna-Barbara Moscicki
Univ of California, San Francisco, US