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 Monday February 26, 2007
Plenary
Feb 26, 2007 8:30 AM

Prevention of HIV Transmission from Breastfeeding
Hoosen Coovadia
Doris Duke Med Res Inst, Univ of KwaZulu Natal, South Africa

Plenary
Feb 26, 2007 9:00 AM

Pathogenesis of AIDS - Connecting Viral Replication to Disease in the Non-Human Primate Model
Louis Picker
Oregon Hlth and Sci Univ, Oregon Natl Primate Res Ctr, Beaverton, US

Oral Abstracts & Scientific Overview: Host-Cell Regulation of Viral Replication
Feb 26, 2007 10:00 AM

Virus Evolution Reveals LEDGF/p75 Is the Sole Mediator of Chromosomal Tethering
Zeger Debyser
Katholieke Univ, Leuven, Belgium

Mechanism of TRIM5a Restriction
Thomas Hope
Feinberg Sch of Med, Northwestern Univ, Chicago, IL, US

Whole Genome Analysis Identifies a Susceptibility Locus to HIV-1
Corinne Loeuillet
Univ Hosp, Univ of Lausanne, Switzerland

Identification and Characterization of Viral MicroRNA Encoded by 2 AIDS-related Opportunistic Herpesviruses
Xuezhong Cai
Duke Univ, Durham, NC, US

HIV-1 Infection Unleashes Retrotransposition of Endogenous Elements
Brad Jones
Univ of Toronto, Canada

7SL RNA Is a Co-factor of the Antiviral Cytidine Deaminase APOBEC3G
Tao Wang
Johns Hopkins Univ Bloomberg Sch of Publ Hlth, Baltimore, MD, US

Oral Abstracts: Issues in Prevention of HIV Transmission and ART
Feb 26, 2007 10:00 AM

Pre-exposure Prophylaxis in Macaques against Rectal SIV Challenge by Mucosally Applied PMPA: Potential for Complementation of Microbicide and Vaccination Strategies
Martin Cranage
St George's, Univ of London, UK

The Effect of Suppressive Acyclovir Therapy on HIV Cervicovaginal Shedding in HIV- and HSV-2-infected Women, Chiang Rai, Thailand
Eileen Dunne
CDC, Atlanta, GA, US

Chlamydial and Gonococcal Infection among Gay and Bisexual Men at the Time of HIV+ Test Result: Implications for Co-treatment, San Francisco, 2004-2006
Katherine Scott
San Francisco Dept of Publ Hlth, CA, US

Potential Effect of ARV Chemoprophylaxis on HIV-1 Transmission in Resource-limited Settings
Ume Abbas
Univ of Pittsburgh, PA, US

Efavirenz vs Nevirapine-based ART Regimens: Adherence and Virologic Outcomes
Jean Nachega
Johns Hopkins Univ, Baltimore, MD, US

Determinants of Mortality among HIV-infected Individuals Receiving Home-based ART in Rural Uganda
David Moore
Global AIDS Prgm, CDC Uganda, Entebbe

Outcomes of Adults Receiving Second-line ART in Médecins Sans Frontières-supported Projects in Resources-limited Countries
Alexandra Calmy
St Vincent's Hosp, Sydney, Australia

Efficacy of Kaletra-based Second-line ART in Cambodia
Laurent Ferradini
Médecins Sans Frontières, Phnom Penh, Cambodia

Oral Abstracts: Metabolic and Cardiovascular Complications of ART
Feb 26, 2007 10:00 AM

HIV-related Immune Suppression after ART Predicts Risk of Non-opportunistic Diseases: Results from the FIRST Study
Jason Baker
Univ of Minnesota, Minneapolis, US and Hennepin County Med Ctr, Minneapolis, MN, US

Metabolic Outcomes of ACTG 5142: A Prospective, Randomized, Phase III Trial of NRTI-, PI-, and NNRTI-sparing Regimens for Initial Treatment of HIV-1 Infection
Richard H. Haubrich
Univ of California, San Diego, US

Ezetimibe's Effects on the LDL Cholesterol Levels of HIV-infected Patients Receiving HAART
David Wohl
Univ of North Carolina at Chapel Hill, US

Poly-L-lactic Acid Injections for Facial Lipoatrophy: A Randomized, Multicenter Trial
Dianne Carey
Natl Ctr for HIV Epidemiology and Clin Res, Univ of New South Wales, Australia

Interruption of ART and Risk of Cardiovascular Disease: Findings from SMART
Andrew Phillips
Royal Free and Univ Coll London Med Sch, UK

Alendronate with Calcium and Vitamin D Supplementation Is Superior to Calcium and Vitamin D Alone in the Management of Decreased Bone Mineral Density in HIV-infected patients: Results of ACTG 5163
Grace McComsey
Case Western Reserve Univ, Cleveland, OH, US

Effects of a Nucleoside Reverse Transcriptase Inhibitor, Stavudine, on Insulin Sensitivity and Mitochondrial Function in Muscle of Healthy Adults
Steven Grinspoon
Massachusetts Gen Hosp, Harvard Med Sch, Boston, US

Significant Sparing of Peripheral Lipoatrophy by HIV Treatment with LPV/r + ZDV/3TC Induction followed by LPV/r Monotherapy Compared with EFV + ZDV/3TC
DW Cameron
Univ of Ottawa at The Ottawa Hosp, Canada

Effects of TH9507, a Growth Hormone Releasing Factor Analog, on HIV-associated Abdominal Fat Accumulation: A Multicenter, Double-blind Placebocontrolled Trial with 412 Randomized Patients
Steven Grinspoon
Massachusetts Gen Hosp, Harvard Med Sch, Boston, US

Oral Abstracts: Pathogenetic Factors Affecting HIV-Specific Immune Responses
Feb 26, 2007 10:00 AM

Superinfection Susceptibility and Low Neutralizing Serum Responses in Treated Persons with Suppressed Plasma Viral RNA Levels
Robert Grant
Gladstone Inst of Virology and Immunology, Univ of California, San Francisco, US

Specific Amino Acids in the N-terminus of the gp41 Ectodomain Contribute to the Stabilization of a Soluble, Cleaved gp140 Envelope Glycoprotein from HIV-1
Antu Dey
Weill Med Coll, Cornell Univ, New York, NY, US

Presence of HLA Class I-associated Cytotoxic T Lymphocyte Escape Mutations in Chronic Untreated HIV Infection Is Significantly Correlated with Clinical Markers of More Severe Disease Progression
Zabrina Brumme
Partners AIDS Res Ctr, Massachusetts Gen Hosp, Boston, US and BC Ctr for Excellence in HIV/AIDS, Vancouver, Canada

Relationship between HLA Genotype and the Functional Profile of Antigen-specific CD8 T Cells
Alexandre Harari
Ctr Hosp Univ Vaudois Lausanne, Switzerland

A Polymorphism in the FγRIIIa Gene Is Associated with HIV Infection Risk
Donald Forthal
Univ of California, Irvine Sch of Med, US

Protective HLA Class I Alleles Select HIV-1 Mutants and Slow Disease Progression
John Frater
The James Martin 21st Century Sch, Oxford Univ, UK

Evidence of a Protective Role for Cytokine/Chemokine Production in HIV Infection
Joseph Casazza
Vaccine Res Ctr, NIAID, NIH, Bethesda, MD, US

Substantial CD4+ T-cell Recovery and Reconstitution of Tissue Architecture in Gut-associated Lymphoid Tissue in Advanced HIV-1 Infection following Initiation of HAART
Derek Shenefelt
Univ of Colorado Hlth Sci Ctr, Denver, US and Weber State Univ, Ogden, UT, US

Oral Abstracts & Scientific Overview: Novel Approaches for Pharmacokinetic Assessment
Feb 26, 2007 4:00 PM

Phenotyping for Drug Interactions: Cocktails Anyone?
Angela Kashuba
Univ of North Carolina at Chapel Hill, US

Concentrations of Lopinavir and Ritonavir in Hair Are Strongly Correlated with Virologic Success
Monica Gandhi
Univ of California, San Francisco, US

Bioequivalence of Pilot Tablet Formulations of Ritonavir to the Marketed Soft Gel Capsule at a Dose of 100 mg
George Hanna
Abbott Labs, Abbott Park, IL, US

Cell-dependent Compartmentalization of Zidovudine- and Lamivudine-triphosphate Concentrations in HIV-seronegative Adults
Peter L. Anderson
Univ of Colorado Hlth Sci Ctr, Denver, US

Symposium: Drivers of the HIV Epidemic and Potential Interventions
Feb 26, 2007 4:00 PM

What's Driving the European HIV Epidemic?
Anne Johnson
Univ Coll London, UK

What's Driving the Global MSM Epidemic?
Frits Van Griensven
CDC Thailand

The STD - HIV Connection from Research to Action: Are We Lost in Translation?
Judith Wasserheit
Univ of Washington, Seattle, US

New HIV Prevention Technologies: What if They Work?
Ward Cates Jr
Family Hlth Intl, Research Triangle Park, NC, US

Symposium: Molecular Co-Factors in HIV Infection
Feb 26, 2007 4:00 PM

Structual Basis for Membrane Targeting by the HIV-1 Gag Protein
Michael Summers
Howard Hughes Med Inst, Univ of Maryland, Baltimore, US

TIP47, a Cellular Cofactor Involved in HIV-1 Envelope Incorporation into Virions
Clarisse Berlioz-Torrent
Inst Cochin, Paris, France

Regulation of HIV-1 Nuclear Entry
Vineet KewalRamani
HIV Drug Resistance Prgm, NCI-Frederick, MD, US

Functions of Apobec3 Complexes and P Bodies
Tariq Rana
Univ of Massachusetts Med Sch, Worcester, US

Symposium: The Latest Concepts in HIV Drug Resistance
Feb 26, 2007 4:00 PM

RTI Mechanisms of Resistance and Interactions that Impact Response
Nicolas Sluis-Cremer
Univ of Pittsburgh Sch of Med, PA, US

Impact of Subtype on HIV Drug Resistance
Jonathan Schapiro
Natl Hemophilia Ctr, Sheba Med Ctr, Tel Hashomer, Israel

Transmission of HIV Drug Resistance and Treatment Response
Susan Little
Univ of California, San Diego, US

Clinical Implications of Low-frequency HIV-1 Variants
Jeffrey Johnson
CDC, Atlanta, GA, US