Greetings from the Program Committee
Mario Stevenson
Univ of Massachusetts Med Sch, Worcester, US

Eleventh Annual Bernard Fields Memorial Lecture: Global HIV-1 Variation and Its Implications for Vaccine Design
Bette Korber
Los Alamos Natl Labs, NM, US

Keynote Lecture: 25 Years of the HIV Pandemic: Lessons Learned
James Curran
Emory Univ Rollins Sch of Publ Hlth, Atlanta, GA, US

Efficacy of a Multigenic DNA/MVA Vaccine to Induce Mucosal Immune Responses and Protect Against Repeated Low Dose Vaginal SIV Challenge
Marie-Claire Gauduin
New England Primate Res Ctr, Harvard Med Sch, Southborough, MA, US

Hepatitis B Surface Antigen Particles Possessing the HIV-1 gp41 Membrane Proximal Region
Sanjay Phogat
Vaccine Res Ctr, Bethesda, MD, US

Neutralization-Sensitive HIV-1 Elicits Stronger Neutralizing Antibody Responses in Individuals with Recent HIV Infection
Simon Frost
Univ of California, San Diego, US

Fcg Receptor IIa and IIIa Polymorphisms Are Associated with the Risk of HIV Infection
Donald Forthal
Univ of California, Irvine Sch of Med, US

Monoclonal Antibody Infusions Delay HIV-1 Rebound after Discontinuation of Antiretroviral Therapy in a Cohort of HIV-1 Infected Individuals Treated during Primary HIV-1 Infection
Saurabh Mehandru
Aaron Diamond AIDS Res Ctr, Rockefeller Univ, NY, NY

Late Breaker: Hexon-Chimeric Adenovirus Serotype 5 Vectors Effectively Circumvent Pre-Existing Anti-Vector Immunity
Dan Barouch
Beth Israel Deaconess Med Ctr, Boston, MA, US

Research Overview: Immune Responses That Successfully Control AIDS Virus Replication
David Watkins
Univ of Wisconsin Med Sch and Wisconsin Natl Primate Res Ctr, Madison, US

Phase I-II Study of a Once-Daily Regimen of Emtricitabine, Didanosine, and Efavirenz in HIV-Infected, Therapy Naïve Children and Adolescents (PACTG Protocol 1021)
Ross McKinney
Duke Univ Sch of Med, Durham, NC, US

Three NRTI HAART Simplification in Children Is Effective in Maintaining Virological and Immunological Control after 108 Weeks
Guido Castelli-Gattinara
Bambino Gesù Children's Hosp and 2Tor Vergata Univ, Rome

Repeated Supervised Treament Interruptions with Progressive Increases in "Off-Treatment" Duration Results in Enhanced Virologic Control in a Subset of Pediatric Individuals
William Borkowsky
New York Univ Sch of Med, New York, US

Dendritic Cell Function in Surviving Children and Adolescents with Long-Term HIV Infection Acquired via Perinatal Route
Seema Desai
Univ of Miami, Miller Sch of Med, FL, US

Prevalence of Primary HIV Drug Resistance among Recently Infected Adolescents: A Multicenter Adolescent Trials Network Study (ATN029)
Rolando Viani
Univ of California, San Diego, US

Incidence of Tuberculosis in HIV-Infected Children: The Influence of Highly Active Antiretroviral Therapy
Neil Martinson
Perinatal HIV Res Unit, Univ of the Witwatersrand, South Africa

Insulin Resistance, Lipodystrophy and Associated Metabolic Changes in HIV-Infected Children
Raffaella Rosso
Univ of Genoa, San Martino Hosp, Italy

Research Overview -- The Price of Antiretroviral Therapy in Children: Focus on Metabolic Morbidities
Grace McComsey
Rainbow Babies and Children's Hosp and Case Western Reserve Univ, Cleveland, OH, US

GS9148: A Novel Nucleotide Active Against HIV-1 Variants with Drug Resistance Mutations in Reverse Transcriptase
Tomas Cihlar
Gilead Sci, Foster City, CA, US

1-(ß-D-Dioxolane)Thymine Is Effective Against HIV-1 Containing TAMs and M184V
Johan Lennerstrand
Emory Univ/VA Med Ctr, Decatur, GA, US

Nucleotide-Competing Reverse Transcriptase Inhibitors form a stable Dead-End-Complex with the HIV-1 Enzyme
Matthias Götte
McGill Univ, Montreal, Canada

Next Generation HIV Peptide Fusion Inhibitor Candidates Achieve Potent, Durable Suppression of Virus Replication In Vitro and Improved Pharmacokinetic Properties
Mary K Delmedico
Trimeris, Inc, Morrisville, NC, US

Late Breaker COMBO: Development of Novel Orally Bioavailable CXCR4 Antagonists, KRH-3955 and KRH-3140: Binding Specificity, Pharmacokinetics, and Anti-HIV-1 Activity in vivo and in vitro
Yuetsu Tanaka
Univ of the Ryukyus, Okinawa, Japan

Late Breaker -- Execution of a High Throughput HIV-1 Replication Screen and the Identification of a Novel Small Molecule Inhibitor that Targets HIV-1 Envelope Maturation
Wade Blair
Pfizer Global Res and Devt, La Jolla, CA, US

Towards Gene Knock Out Therapy for AIDS/HIV: Targeted Disruption of CCR5 Using Engineered Zinc Finger Protein Nucleases
Elena Perez
University of Pennsylvania, Philadelphia, PA

Pharmacokinetics/Pharmacodynamics of PA-457 in a 10-Day Multiple Dose Monotherapy Trial in HIV-Infected Patients
Patrick Smith
Univ at Buffalo Sch of Pharmacy, Buffalo, NY, US

Research Overview: The Role of Drug Interaction Studies in Early Antiretroviral Drug Development
Kimberly Struble
Ctr for Drug Evaluation and Res, Food and Drug Admin, Silver Spring, MD, US

Lack of Neutralizing Antibody Response to HIV-1 Predisposes to Superinfection
Davey Smith
Univ of California, San Diego, US

Broad Neutralization of HIV-1 Variants in Couples without Evidence of Systemic Superinfection Despite Exposure
Robert Grant
David Gladstone Insts, San Francisco, CA, US

Non-Neutralizing Antibody that Prevents SIV Infection in Neonatal Rhesus Macaques Potently Inhibits SIV in the Presence of Rhesus Macaque Effector Cells
Donald Forthal
Univ of California, Irvine Sch of Med, US

Simian Immunodeficiency Virus Engrafted with HIV-1-Specific Epitopes: Replication, Neutralization and Survey of HIV-1-Positive Plasma
Welkin Johnson
New England Primate Res Ctr, Harvard Med Sch, Southborough, MA, US

Defining and Measuring HIV-1 Escape from CTL: Epitope-Dependent Avidity Thresholds
Otto Yang
Univ of California, Los Angeles, US

Localized Populations of CD8- SIV-Specific T Cells in Lymphoid Follicles and Vaginal Epithelium
Pamela Skinner
Univ of Minnesota, St Paul, US

Maintenance of HIV-Specific CD4+ T-Cell Help Distinguishes HIV-2 from HIV-1 Infection
Melody Duvall
MRC Human Immunology Unit, Weatherall Inst of Molecular Med, Oxford, UK

Research Overview -- Immune Control of HIV Infection: Predictability in the Midst of Chaos
Bruce Walker
Partners AIDS Res Ctr, Harvard Med Sch, Boston, MA, US

High Cerebrospinal Fluid Neurofilament Protein Levels in AIDS Dementia Complex
Magnus Gisslén
Sahlgrenska Akademy at Göteborg Univ, Sweden

Leptin and Neuropsychological Performance: A New Biomarker for Cognitive Function?
Jeannie Huang
Univ of California, San Diego, US

Better Antiretroviral Penetration into the Central Nervous System Is Associated with Lower CSF Viral Load
Scott Letendre
Univ of California, San Diego, US

Discordance of Genotypic Resistance between CSF and Plasma Virus in a Multicenter Observational Cohort
Joseph Wong
VA Med Ctr San Francisco, CA US

The HIV Env N283 Genetic Variant Is Associated with Brain Infection and Dementia
Rebecca Dunfee
Dana-Farber Cancer Inst, Boston, MA, US and Harvard Med Sch, Boston, MA, US

Longitudinal Analysis of env Population Dynamics in Blood and Cerebrospinal Fluid of SIVsm-Infected Macaques
Patrick Harrington
Univ of North Carolina Sch of Med, Chapel Hill, US

Hemochromatosis Gene Polymorphisms and Peripheral Neuropathy during Antiretroviral Therapy: Analysis NWCS 238 of ACTG Study 384
Asha R Kallianpur
Vanderbilt Univ Sch of Med, Nashville, TN, US

Controlled Study of High-Concentration Capsaicin Patch for Painful HIV-Associated Distal Sensory Polyneuropathy
David Simpson
Mount Sinai Med Ctr, New York, NY, US

Research Overview: Update on Sensory Neuropathies
Justin McArthur
Johns Hopkins Univ Sch of Med, Baltimore, MD, US

Predictors of HIV Disease Progression in Patients Who Stop Antiretroviral Therapy with CD4 Cell Counts > 350 cells/mm3 (ACTG 5170)
Daniel Skiest
Baystate Med Ctr, Springfield, MA, US

CD4-Guided Scheduled Treatments Interruptions Compared to Continuous Therapy: Results of the Staccato Trial
Jintanat Ananworanich
HIV-NAT, Bangkok, Thailand

ISS PART: Final Results of a Randomized, Controlled Trial of Structured Treatment Interruptions versus Continuous HAART in Chronic HIV-Infected Subjects with Persistent Suppression of Viral Replication
Lucia Palmisano
Inst Superiore di Sanità, Rome, Italy

Structured Treatment Interruptions in HIV-Infected Patients with High CD4 Cell Counts and Virologic Suppression: Results of a Prospective, Randomized, Open-Label Trial (Window - ANRS 106)
Bruno Marchou
Hosp Purpan, Toulouse, France

Late Breaker - The CD4-guided Strategy Arm Stopped in a Randomized Structured Treatment Interruption (STI) Trial in West-African Adults: ANRS 1269 Trivacan Trial
Christine Danel
CHU de Treichville, Abidjan, Côte d'Ivoire

Late Breaker - Episodic CD4-Guided Use of Antiretroviral Therapy is Inferior to Continuous Therapy: Results of the SMART Study.
Wafaa El-Sadr and James Neaton
for the SMART Study Investigators

Late Breaker - Efficacy and Safety of Atazanavir-Based Therapy in Antiretroviral Naive HIV-1 Infected Subjects, Both With and Without Ritonavir: 48-Week Results from AI424-089
Niel Malan
Triple M Res, Port Elizabeth, South Africa

Late Breaker - A Prospective, Open-Label, Pilot Trial of Regimen Simplification to Atazanavir/Ritonavir Alone As Maintenance Antiretroviral Therapy After Sustained Virologic Suppression (ACTG 5201)
Susan Swindells
Univ of Nebraska Med Ctr, Omaha, US

Late Breaker - Safety of Nevirapine Compared to Abacavir on a Background of Zidovudine/Lamivudine as First-line Antiretroviral Therapy: a Randomised Double-Blind Trial
Paula Munderi
MRC/UVRI Uganda Res Unit on AIDS, Entebbe

Viral Decay Rates in Men and Women Receiving Triple-Nucleoside or Efavirenz -Containing Antiretroviral Therapy: Viral Dynamics Substudy of ACTG A5095
Kathleen Squires
Thomas Jefferson Univ, Philadelphia, PA

Early Clinical Toxicity to Nonnucleoside Reverse Transcriptase Inhibitor-Based Highly Active Antiretroviral Therapy in a Home-Based AIDS Care Program in Rural Uganda
Fatu Forna
Ctrs for Disease Control and Prevention, Atlanta, GA, US

Adverse Events in HIV-Infected Patients Receiving Antiretroviral Therapy in a Treatment Program in a Nairobi Slum, Kenya, 2003 - 2005
Andrea A Kim
Ctrs for Disease Control and Prevention, Atlanta, GA, US

Exposure to PIs and NNRTIs and Risk of Myocardial Infarction: Results from the D:A:D Study
Nina Friis-Møller
Copenhagen HIV Prgm (CHIP), Hvidovre Univ Hosp, Copenhagen, Denmark

Three-Year Follow-Up of Carotid Intima-Media Thickness in HIV-Infected and Uninfected Adults: ACTG 5078
Judith Currier
Univ of California Los Angeles CARE Ctr, US

The Safety and Efficacy of Fish Oil in Combination with Fenofibrate in Subjects on ART with Hypertriglyceridemia who had an Incomplete Response to Either Agent Alone: Results of ACTG A5186
John G Gerber
Univ of Colorado Hlth Sci Ctr, Denver, US

Effects of Metformin and Rosiglitazone on Body Composition in HIV-Infected Patients with Hyperinsulinemia and Elevated Waist/Hip Ratio: A Randomized, Placebo Controlled Trial
Kathleen Mulligan
Univ of California, San Francisco, US

A Randomized Placebo-Controlled Trial of Metformin for the Treatment of HIV Lipodystrophy
Rakhi Kohli
Tufts Univ Sch of Med Boston, MA, US

Effects of Physiologic Testosterone Supplementation on Fat Mass and Distribution in HIV-Infected Men with Abdominal Obesity: ACTG 5079
Cecilia Shikuma
Univ of Hawaii, Honolulu, US

Randomized, Placebo Controlled Trial of Valganciclovir to Prevent CMV End-Organ Disease among HIV-Infected Subjects with Detectable Plasma CMV DNA PCR - ACTG 5030
David Wohl
Univ of North Carolina at Chapel Hill, US

Late Breaker: Effect of Pioglitazone on HIV-1 Related Lipoatrophy: A Randomized Double-Blind Placebo-Controlled Trial (ANRS 113) with 130 Patients
Willy Rozenbaum
Tenon Hosp, Paris, France and Saint Louis Hosp, Paris, France

Molecular Mechanism of Tenofovir, Abacavir and Lamivudine Resistance by the K70E Mutation in HIV-1 Reverse Transcriptase
Nicolas Sluis-Cremer
Univ of Pittsburgh, PA, US

Clonal Analysis of HIV-1 Quasispecies Enables Unambiguous Identification of the Genetic Determinants of Various Phenotypic Properties of the Envelope Proteins
Jonathan Toma
Monogram Biosci, South San Francisco, CA, US

Effect of Baseline Resistance on the Virologic Response to a Novel NNRTI, TMC125, in Patients with Extensive NNRTI and PI Resistance: Analysis of Study TMC125-C223
Johan Vingerhoets
Tibotec, Mechelen, Belgium

Distinct Patterns of Sequence Variation in HIV-1 pro and pol in Chronically Infected Antiretroviral-Naïve Individuals
Frank Maldarelli
NCI-Frederick, Frederick MD US

Viral Resistance to PA-457, a Novel Inhibitor of HIV-1 Maturation
Catherine Adamson
HIV Drug Resistance Prgm, Natl Cancer Inst, Frederick, MD, US

Effect of Baseline Susceptibility and On-Treatment Mutations on TMC114 and Control PI Efficacy: Preliminary Analysis of Data from PI-Experienced Patients from the POWER 1 and POWER 2
MP De Bethune
Tibotec BVBA, Mechelen, Belgium

Late Breaker Combo: In Vitro Characterization of HIV Isolated from Patients Treated with the Entry Inhibitor TNX-355
Thomas Duensing
Tanox, Inc, Houston, TX, US

Late Breaker: Potent Antiretroviral Effect of MK-0518, a Novel HIV-1 Integrase Inhibitor, in Patients with Triple-class Resistant Virus
Beatriz Grinsztejn
Evandro Chagas Clin Res Inst/Oswaldo Cruz Fndn, Rio de Janeiro, Brazil

Late Breaker: The HIV Integrase Inhibitor GS-9137 (JTK-303) Exhibits Potent Antiviral Activity in Treatment-Naïve and Experienced Patients
Edwin DeJesus
Orlando Immunology Ctr, FL, US

Late Virologic Breakthrough in Treatment Naive Patients on a Regimen of Combivir (CBV) + Vicriviroc
Wayne Greaves
Schering Plough Res Inst, Kenilworth, NJ, US

Natural Reservoirs of Chimpanzee Lentiviruses Closely Related to HIV-1 Groups M and N
Fran Van Heuverswyn
IRD and Univ of Montpellier, France

Langerhans Cells Mediate HIV Trans-Infection of Target Cells
Kelly M Fahrbach
Northwestern Univ Med Sch, Cell and Molecular Biology Dept, Chicago, IL, US

Non Macrophage-Tropic R5 Envelopes Predominate in Blood, Lymph Node and Semen: Implications for Transmission and Pathogenesis
Paul Clapham
Univ of Massachusetts Med Sch, Worcester, US

Mutation of HIV-1 Gag Relieves the Early, Postentry Block by Pre-mRNA Factor CPSF6
Zandrea Ambrose
Natl Cancer Inst, Frederick, MD, US

Selective Destruction of the HIV-1 Capsid Shell by the Restriction Factor TRIM5 Alpha
Philippe Gallay
The Scripps Res Inst, La Jolla, CA, US

Multiple Cytoplasmic Human Tripartite Motif Proteins Block Human Immunodeficiency Virus Replication
Aine McKnight
Univ Coll London, UK

Multiple APOBEC3 Family Cytidine Deaminases Are Potent Inhibitors of Mammalian Retrotransposons
Hui Chen
The Salk Inst, La Jolla, CA, US

Regulated Formation of HIV-1 Vif-Cul5 E3 Ubiquitin Ligase through a Novel Zinc-Binding Domain-Stabilized Hydrophobic Interface in Vif
Elana Ehrlich
Johns Hopkins Bloomberg Sch of Publ Hlth, Baltimore, MD US

Late Breaker: Overexpression of the LEDGF/p75 Integrase Binding Domain Abrogates HIV-1 Replication
Zeger Debyser
Molecular Med,Catholic Univ Leuven, Belgium

Late Breaker: Balancing Selection, Gene Duplication and Functional Polymorphism in the Rhesus Macaque and Sooty Mangabey TRIM5alpha Locus
Welkin Johnson
New England Primate Res Ctr, Harvard Med Sch, Southborough, MA, US

Utility of the Early Viral Response to Individually-Adjust the Duration of Treatment for Chronic Hepatitis C, Genotype 2 or 3, in HIV-Coinfected Patients
Manel Crespo
Vall d'Hebron's Hosp, Barcelona, Spain

Serum IP-10 Level Is Associated with Distinct Early Viral Dynamics in HCV and HCV-HIV Infected Subjects Treated with IFN-a
Benigno Rodriguez
Case Western Reserve Univ Ctr for AIDS Res

Effects of Cytokine Gene Polymorphisms on Treatment of Acute Hepatitis C Infection in HIV-Infected Patients
Jacob Nattermann
Dept of Internal Med I, Univ of Bonn, Germany

Virus-Specific T-Cell Responses and Loss of Spontaneous Control of HCV in HIV+ Individuals
Arthur Kim
Harvard Med Sch, Massachusetts Gen Hosp, Boston, US

Enhanced Replication of GB Virus C in HIV-Infected Patients Receiving Highly Active Antiretroviral Therapy
Per Björkman
Malmo Univ Hosp, Sweden and 2Lund Univ Hosp, Sweden

Evidence for Sexual Transmission of HCV in Recent Epidemic in HIV-Infected Men in the UK
Mark Danta
Royal Free and Univ Coll Med Sch, London, UK

Rise in HCV Incidence in HIV-infected Men Who Have Sex with Men in Amsterdam: Sexual Transmission of Difficult to Treat HCV Genotypes 1 and 4
Thijs van de Laar
Amsterdam HCV Study Group, The Netherlands

Systemic Overview of HAART-Associated Liver Enzyme Elevations (LEE) in Patients Infected with HIV and Coinfected with HCV
Yves Benhamou
Hosp Pitie Salpetriere, Paris, France

Adherence to NNRTI-Based Regimens and Virologic Outcomes in HIV-Infected South African Adults
Jean Nachega
Johns Hopkins Univ, Dept of Intl Hlth, Baltimore, MD, US

Mortality and Causes of Death in Adults Receiving HAART in Senegal: A 7-Year Cohort Study
Eric Delaporte
Inst for Res and Devt and Univ of Montpellier, France

Rapid Scale-Up of Antiretroviral Services in Zambia: 1-Year Clinical and Immunologic Outcomes
Moses Sinkala
Zambian Ministry of Hlth, Lusaka, Zambia

Performance Characteristics of Non-CD4 based Criteria for Initiation of Antiretroviral Therapy in an Ambulatory Clinic Population in Phnom Penh, Cambodia
Chel Sarim
Natl Ctr for HIV/AIDS, Dermatology and STIs Ministry of Hlth Cambodia

Regimen Durability and Tolerability to 36 Months Duration on ART in Khayelitsha, South Africa
Andrew Boulle
Sch of Publ Hlth and Family Med, Univ of Cape Town, South Africa

When Are Adults in Resource-Constrained Settings most likely to Experience an HIV-Associated Illness following HAART Initiation and What Is It Related To?
Paula Braitstein
Univ of Berne, Switzerland

Tuberculosis among HIV-Infected Patients Receiving HAART: Long-Term Incidence and Risk Factors in a South African Cohort
Stephen Lawn
Desmond Tutu HIV Ctr, Univ of Cape Town, South Africa and London Sch of Hygiene and Tropical Med, UK

Prevalence of HIV and Undiagnosed Tuberculosis in a Periurban Community in South Africa
Linda-Gail Bekker
The Desmond Tutu HIV Ctr, Univ of Cape Town, South Africa

Late Breaker: Evidence for Persistent, Occult Infection in Neonatal Macaques following Perinatal Transmission of SHIV-SF162P3
Nancy Haigwood
Seattle Biomed Res Inst, WA, US and Univ of Washington, Seattle, US

Identification of a Human Milk Glycoprotein that Binds DC-SIGN and Inhibits HIV-1 Transfer to CD+ T-Lymphocytes
Marloes Naarding
Academic Med Ctr, Amsterdam, Netherlands

Evidence for Distinct Mechanisms for Intrauterine and Intrapartum HIV Mother-to-Child Transmission
Elizabeth Russell
Dept of Microbiology and Immunology, Univ of North Carolina at Chapel Hill, US

Effectiveness of Repeat Single-Dose Nevirapine in Subsequent Pregnancies among Ugandan Women
Paul Bakaki
Ctrs for Disease Control and Prevention, Atlanta, GA, US

Cotrimoxazole Prophylaxis and Adverse Birth Outcomes among HIV-Infected Women in Lusaka, Zambia
Jan Walter
Columbia Univ, New York, NY, US

Rapid HIV Testing and Prevention of Mother-to-Child HIV Transmission in High-Risk Maternity Hospitals, St Petersburg, Russia, 2004-2005
Dmitry Kissin
CDC, Atlanta, GA, US

Male Circumcision and the Risks of Female HIV and STI Acquisition in Rakai, Uganda
Steven Reynolds
Johns Hopkins Univ, Bloomberg Sch of Publ Hlth, Baltimore, MD, US

First Dose and Steady-State Genital Tract Pharmacokinetics of Ten Antiretroviral Drugs in HIV-Infected Women: Implications for Pre- and Post- Exposure Prophylaxis
Julie Dumond
Univ of North Carolina at Chapel Hill, US

Initiation of Antiretroviral Therapy Leads to a Rapid Decline in Cervical and Vaginal HIV-1 RNA
Susan Graham
Univ of Washington, Seattle, US

Infection with Trichomonas vaginalis Increases the Risk for HIV-1 Acquisition: A Prospective Study
R Scott McClelland
Univ of Washington, Seattle, US and Univ of Nairobi, Kenya

Routine HIV Testing in Botswana: A Population-Based Study on Attitudes, Practices, and Human Rights Concerns
Sheri Weiser
Ctr for AIDS Prevention Studies, Univ of California, San Francisco, US

HLA-B Bw4 and Bw6 Alleles and Risk for HIV-1 Transmission in HIV-Serodiscordant Heterosexual Couples
Tania M Welzel
Natl Cancer Inst, Rockville, MD, US

Trends in HIV Diagnosis among Non-Hispanic Black Americans, 2001-2004
Tonji Durant
CDC, Atlanta, GA, US

High HIV Prevalence and Incidence Observed among African-American Men who have Sex with Men in Baltimore: The Behavioral Surveillance Research (BESURE) Study
Frangiscos Sifakis
Johns Hopkins Bloomberg Sch of Publ Hlth, Baltimore, MD, US

Non-AIDS Related Mortality Risk Exceeds AIDS-Related Mortality among Injecting Drug Users with CD4+ Counts Above 200 Cells/mm3
Bryan Lau
Johns Hopkins Univ Sch of Med, Baltimore, MD, US and Johns Hopkins Bloomberg Sch of Publ Hlth, Baltimore, MD, US

Primary Causes of Mortality in HIV Discordant Zambian Couples
Philip J Peters
Rwanda-Zambia HIV Res Group

Late Breaker -- National HIV Prevalence and BED HIV Incidence Estimates: South Africa 2005
Thomas Rehle
Human Sci Res Council, Cape Town, South Africa

Late Breaker -- Prevention of Rectal SHIV Transmission in Macaques by Tenofovir/FTC Combination
Walid Heneine
CDC, Atlanta, GA, US

Late Breaker -- Impact of HSV2 Suppressive Therapy on HIV-1 Genital Shedding and Plasma Viral Load: a Proof of Concept Randomised Double-Blind Placebo Controlled Trial (ANRS 1285 Trial)
Nicolas Nagot
London Sch of Hygiene & Tropical Med, UK

Late Breaker -- Association between Genital Schistosomiasis and HIV in Rural Zimbabwean Women
Eyrun F Kjetland
Ctr for Imported and Tropical Diseases, Ulleval Univ Hosp, Oslo, Norway

Investigation of Reports of Excessive False-positive Oral Fluid Rapid HIV Tests
Bernard Branson
Ctrs for Disease Control and Prevention, Atlanta, GA, US

Dramatic CD4+ T-Cell Depletion in the Intestine Is a Hallmark of SIV Infection in Natural Hosts
Ivona Pandrea
Tulane Natl Primate Res Ctr, Covington, LA, US

High Frequencies of Infected CD4+ T Cells in GI Tract Is Associated with Poor Mucosal Immune Reconstitution after HAART
Jason Brenchley
Vaccine Res Ctr, NIAID, NIH, Bethesda, MD, US

Initiation of HAART during Primary HIV-1 Infection Results in Better Restoration and Maintenance of Mucosal CD4+ T Cells
Satya Dandekar
Univ of California, Davis, US

Restoration of Memory CD4+ CCR5+ T Cells in the Gastrointestinal Tract during the Chronic Stage of SIV Infection Predicts Long-Term Non-Progression
Binhua Ling
Tulane Natl Primate Res Ctr, Covington, LA, US

CD4+ T-Cell Quantification within Gut Lamina Propria of HIV Patients after HAART
Jason Baker
Dept of Med at Univ of Minnesota

AIDS Defining CD4 T-Cell Levels Correlate with Expanded Coreceptor Usage (R5/X4) during Nonpathogenic SIVsm Infection of Sooty Mangabeys
Jeffrey Milush
Univ of Texas Southwestern Med Ctr, Dallas, US

CXCR4-Tropic Viruses Are Common among Antiretroviral-Treated Patients with Detectable Viremia and Associated with Lower Treatment-Mediated CD4 Gains
Peter Hunt
Univ of California, San Francisco, US

Late Breaker -- The Effect of HIV Subtype on Rapid Disease Progression in Rakai, Uganda
Oliver Laeyendecker
NIAID, NIH and the Johns Hopkins Med Inst, Baltimore, MD, US

Lessons Learned from In Vitro Cultivation of Hepatitis C
Takaji Wakita
Tokyo Metropolitan Inst for Neurosci, Japan

Ten Years of HAART: Principles for the Future
John G Bartlett
Johns Hopkins Univ Sch of Med, Baltimore, MD, US

Where AIDS Came From
Paul Sharp
Inst of Genetics, Univ of Nottingham, Queen's Med Ctr, UK

AIDS Restriction Genes: Discovery, Assessment and Implications
Stephen O'Brien
Lab of Genomic Diversity, NCI, Frederick, MD, US

Circumcision and HIV Transmission: The Cutting Edge
Tom Quinn
NIAID, NIH and Johns Hopkins Univ, Baltimore, MD, US

Preventing HIV Transmission by Topical Microbicides
John Moore
Cornell Univ, Weill Med Coll, New York, NY, US

HIV Molecular Virology: Mechanisms of Evasion
Ned Landau
The Salk Inst for Biological Studies, La Jolla, CA, US

Principles of HIV Disease Pathogenesis
John Coffin
NCI Drug Resistance Prgm, Frederick, MD, US

Advances in Eliciting HIV-Specific Immunity
Richard Koup
Vaccine Res Ctr, NIAID, NIH, Bethesda, MD, US

NIH Funding Opportunities for Young Investigators
Opendra Sharma
NIAID, NIH, Bethesda, MD, US

New Developments in Antiretroviral Therapy
Scott Hammer
Columbia Univ Coll of Physicians and Surgeons, New York, NY, US

Pathogenesis and Management of HIV Complications
Judy Currier
David Geffen Sch of Med, Univ of California, Los Angeles, US

Hepatitis C Virus: A Wily and Redoubtable Foe as the HIV
T Jake Liang
NIDDK, NIH, Bethesda, MD, US

Current Challenges in the Clinical Management of HIV/HCV Co-Infection
Stuart Ray
Viral Hepatitis Ctr, Johns Hopkins Univ, Baltimore, MD, US

HCV Protease Inhibitors: Activity and Resistance
Ann Kwong
Vertex Pharmaceuticals, Cambridge, MA, US

HCV Polymerase Inhibitors: Multiple Shots on Goal
Daria Hazuda
Merck Res Labs, West Point, PA, US

HIV and Malaria-When Elephants Collide
Laurence Slutsker
Kenya Med Res Inst Res Station, Kisumu

HIV and Tuberculosis
Anthony Harries
Malawi Ministry of Hlth, Lilongwe

Prevention of Pneumococcal Disease in HIV Infected Adults and Children
Keith Klugman
Emory Univ, Atlanta, GA, US

HIV and Cancer
Robert Newton
Univ of York, UK

Quantifying the Impact of Primary Infection on HIV Transmission and Control
Christophe Fraser
Imperial Coll London, UK

HIV Serosorting among Men who Have Sex with Men: Implications for Prevention
Matthew Golden
Univ of Washington Ctr for AIDS and STDs, Seattle, US

Normalizing HIV Testing in Health Care Settings
Timothy Mastro
CDC, Atlanta, GA, US

Prevention in HIV Clinical Settings
Jean L Richardson
Keck Sch of Med, Univ of Southern California, Los Angeles, US

After the Acute Phase: Infection and Depletion in Treated and Untreated Chronic HIV Infection
Daniel Douek
Vaccine Res Ctr, NIAID, NIH, Bethesda, MD, US

Persistence of SIV in the Intestine of Treated or Immunized Macaques
Ronald Veazey
Tulane Natl Primate Res Ctr, Covington, LA, US

HIV Reservoirs in the Era of Effective Antiviral Therapy: Perspectives for Eradication and New Therapeutic Strategies
Tae-Wook Chun
NIAID, NIH, Bethesda, MD, US

Long-Term Persistence of Low-Level HIV-1 in Patients on Suppressive Antiretroviral Therapy
John Coffin
Drug Resistance Prgm, NCI, Frederick, MD, US

Implications of Early Events in HIV Infection for Treatment: Back to the Future?
Jeff Lifson
NCI, SAIC, Frederick, MD, US

Sex, Drugs and ... Outcome on Therapy
Monica Gandhi
Univ of California, San Francisco, US

Limiting the Limitations of Antiretrovirals
Andrew Carr
St Vincent's Hosp, Sydney, Australia

New Agents and Treatment Paradigms: Navigating through the Drug Development Mine Field
Michael Saag
Univ of Alabama at Birmingham, US

HIV Infection of Non-Dividing Cells
Michael Emerman
Univ of Washington Sch of Med and Fred Hutchinson Cancer Res Ctr, Seattle, US

Restriction of Retrovirus Replication
Jonathan Stoye
Natl Inst for Med Res, Med Res Council, London, UK

Evolution of Intrinsic Immunity against Retroviruses in Primate Genomes
Harmit Malik
Fred Hutchinson Cancer Res Ctr, Seattle, US

New Insights into the Antiviral Action of APOBEC
Warner Greene
Gladstone Inst, Univ of California, San Francisco, US

Antiretroviral Therapy to Prevent Sexual Transmission of HIV
Myron Cohen
Univ of North Carolina at Chapel Hill, US

Beyond Condoms: Chemical and Physical Barriers to Protect Women from HIV
Sharon Hillier
Univ of Pittsburgh Sch of Med, Magee-Womens Hosp,PA, US

Vaccines to Induce CTL Responses to HIV in Immunocompetent Individuals: State of the Field
Lawrence Corey
HIV Vaccine Trials Network, Fred Hutchinson Cancer Res Ctr, Seattle, US

HIV Voluntary Testing and Counseling (VCT) Divides, But It Should Unite
Thomas Coates
Univ of California, Los Angeles, US

In Vitro Affinity Maturation of the HIV-1 Broadly Neutralizing Anti-gp41 Antibody Z13
Michael Zwick
The Scripps Res Inst, La Jolla, CA, US

Potential Difficulties in Eliciting Antibodies to the Membrane Proximal Region of HIV-1
Barton Haynes
Human Vaccine Inst, Duke Univ, Durham, NC, US

The Membrane Proximal External Region of HIV-1 on Different Viral Scaffolds: Detection of Epitope-specific Neutralizing Antibodies
George Shaw
Univ of Alabama at Birmingham and Howard Hughes Med Inst, US

Lessons from the Use of Membrane Proximal External Region Antibodies in vivo
Alexandra Trkola
Univ Hosp Zurich, Switzerland